Biodesign.

Bioconvergence.

Biosimulation.

Case Studies

We know how important it is to have a model that is as close to the clinical setting as possible. BioSim Innovations' design development team focuses on the anatomy, physiology, and engineering required to develop models to bring your finished medical device to market successfully.

Mitral Valve Repair

Challenge

Mitral valve regurgitation

Solution

Beating animal and human heart with IVC access, transseptal crossing, cut chords, valve flail, regurgitation, and physiological pressures

Calcified Vessels

Challenge

Arterial calcifications

Solution

Use microCT to identify calcium modifications after a procedure

Neuro Tracking

Challenge

Device delivery to brain

Solution

Perfusion from device access site to neural region in human/animal tissue

Femoral Access / Pelvic Dip

Challenge

Tracking from the femoral access to heart

Solution

Creating a tortious path that mimics native architecture

Aortic Valve Replacement

Challenge

Aortic arch with functioning aortic valve

Solution

Beating heart with either native or 3D printed aortic arch and descending aorta with and without calcification

Cellular Response

Challenge

Assess whether cells respond to a device modification

Solution

In vitro model that mimics the relevant cellular environment